pentobarbital will minimize the extent or result of netupitant/palonosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Netupitant is principally metabolized by CYP3A4; stay away from use in individuals who will be chronically employing a robust CYP3A4 inducerEven though it may be used being a s